Acid-catalyzed synthesis of bicyclo[3.n.1]alkenediones |
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| Authors: | Michaelides Iacovos N Darses Benjamin Dixon Darren J |
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| Affiliation: | Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK. |
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| Abstract: | ![]()
An acid-catalyzed Dieckmann-type reaction has been developed to access functionalized bicyclo[3.2.1]alkenediones. This methodology has been successfully extended to more substituted and larger ring homologues, providing a new and efficient route to the core of numerous attractive natural products and their analogues. |
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