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Simple and efficient one‐pot synthesis of 3,4‐dihydro‐2‐pyridones via solid‐supported Bi(III)nitrate catalyzed double michael addition‐azaannulation
Authors:Jagjeet Singh  Summon Koul  Rattan L. Sharma  Tej K. Razdan  Ajay P. S. Pannu
Affiliation:1. Department of Chemistry, University of Jammu, Ambedkar Road, Jammu‐180006, India;2. Department of Chemistry, G. N. D. University, Amritsar, Punjab 154003, India
Abstract:
chemical structure image 4‐Aryl‐5‐carboethoxy‐6‐methyl‐2,3‐dihydro‐2‐pyridones were obtained, in high yield, by heating ternary mixtures of appropriate aldehydes, ethylacetoacetate and compounds possessing NH2‐C=X functionality, in presence of immobilized Bi(III)nitrate and co‐catalyst Zn(II)chloride, under solventless conditions. The reaction proceeds smoothly at 140±5°C and seems to involve double Michael addition‐azaannulation.
Keywords:
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