Macrorhynines A and B,Two Novel Norditerpenoid Alkaloids from Aconitum macrorhynchum |
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| Authors: | Xiao‐Dong Yang Shu Yang Jin Yang Jing‐Feng Zhao Hong‐Bin Zhang Liang Li |
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| Affiliation: | 1. Key Laboratory of Medicinal Chemistry for Natural Resources (School of Chemical Science and Technology, Yunnan University), Ministry of Education, Kunming 650091, P.?R. China, (phone: +86‐871‐5033644‐8899;2. fax: +86‐871‐5035538);3. College of Fundamental and Information Engineering, Yunnan Agricultural University, Kunming 650201, P.?R. China;4. Department of Chemistry, Honghe University, Mengzi 661100, P.?R. China |
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| Abstract: | Two novel norditerpenoid alkaloids, macrorhynines A and B ( 1 and 2 ), together with seven known compounds, were isolated from Aconitum macrorhynchum. The structures of the new compounds were elucidated as (1α,6α,14α)‐8‐acetoxy‐1,6,16‐trimethoxy‐4‐(methoxymethyl)aconitan‐14‐yl 4‐methoxybenzoate ( 1 ) and (1α,6α,14α)‐8‐acetoxy‐13‐hydroxy‐1,6,16‐trimethoxy‐4‐(methoxymethyl)aconitan‐14‐yl 4‐methoxybenzoate ( 2 ) on the basis of spectral analyses. The novel compounds were found to contain the rare C(19)?N, azomethine, group. |
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| Keywords: | Macrorhynines A and B Norditerpenoid alkaloids Alkaloids Aconitum macrorhynchum |
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