1. Nucleic Acid Center Department of Physics and Chemistry, University of Southern Denmark, Campusvej 55, DK‐5230 Odense M, Denmark;2. Dipartimento di Scienze e Tecnologie Biomediche, Sezione di Microbiologia e Virologia Generale e Biotecnologie Microbiche, Universitá di Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy
Abstract:
1,5‐Disubstituted pyrimidine‐2,4‐diones were synthesized by fusion of 5‐bromouracil with an aniline derivative followed by coupling with benzyl halide whereas the opposite synthesis sequence failed. Also 4,6‐dichloro‐N,N,5‐trimethylpyrimidin‐2‐amine was treated with phenols. The products were tested for their activity against HIV‐1.
