Five New Eremophilane Sesquiterpenes from Ligularia przewalskii |
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| Authors: | Ji‐Qing Xu Li‐Hong Hu |
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| Affiliation: | 1. Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, P.?R. China;2. School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P.?R. China, (phone: +86‐21‐50272221;3. fax: +86‐21‐50272221) |
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| Abstract: | Five new eremophilane‐type sesquiterpenes, 3β‐(acetyloxy)‐7‐hydroxynoreremophila‐6,9‐dien‐8‐one ( 1 ), 8β‐hydroxy‐2‐dehydroxyliguhodgsonal ( 2 ), 3β‐(acetyloxy)‐11‐methoxy‐8‐oxoeremophila‐6,9‐dien‐12‐oic acid ( 3 ), 3β‐(acetyloxy)‐11‐(2′‐methylbutanoyloxy)‐8‐oxoeremophila‐6,9‐dien‐12‐oic acid ( 4 ), and 3β‐(acetyloxy)‐6α‐hydroxyligularenolide ( 5 ), along with the three known compounds 6 – 8 , were isolated from the roots of Ligularia przewalskii. The structures of the new compounds were elucidated through spectral studies including HR‐EI‐MS, IR, and NMR data. |
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| Keywords: | Eremophilanes Sesquiterpenes Ligularia przewalskii |
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