Molecular Iodine Catalyzed One‐pot Aza‐Diels‐Alder Reaction under Solvent‐free Conditions |
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| Authors: | Shu‐Su SHEN Shun‐Jun JI |
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| Affiliation: | 1. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, Suzhou, Jiangsu 215123, China;2. Tel.: 0086‐0512‐65880086;3. Fax: 0086‐0512‐65880307 |
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| Abstract: | Catalyzed by molecular iodine at room temperature, under solvent‐free conditions, a two component aza‐Diels‐Alder cyclization of N‐vinyl‐2‐pyrrolidinone with N‐arylimine gave tetrahydroquinoline derivatives in good yields and high stereo‐selectivity. And three components aza‐Diels‐Alder reaction of N‐vinyl‐2‐pyrrolidinone, anilines and indole‐3‐carbaldehydes under the same condition afford only cis‐product in good yields. |
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| Keywords: | aza‐Diels‐Alder reaction iodine solvent‐free tetrahydroquinoline |
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