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Synthesis of new condensed derivatives of pyrano[4,3-<Emphasis Type="Italic">b</Emphasis>]thieno[3,2-<Emphasis Type="Italic">e</Emphasis>]pyridine and pyrido[3',2':4,5]thieno[3,2-<Emphasis Type="Italic">d</Emphasis>]pyrimidine
Authors:V V Dabaeva  M R Bagdasaryan  A S Noravyan
Institution:(1) A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, 26 Azatutyan Ave., Yerevan, 0014, Armenia;
Abstract:The reactions of 2-methyl (propyl) substituted 8,8-dimethyl-7,10-dihydro-4H,8H-pyrano3",4":5',6']pyrido3',2':4,5]thieno3,2-d]1,3]oxazines with primary amines give 2-methyl (propyl) substituted 8,8-di- methyl-7,10-dihydro-8H-pyrano3",4":5',6']pyrido3',2':4,5]thieno3,2-d]1,3]pyrimidin-4(3H)-ones or 3-acetyl-N-alkyl- and N-alkyl-3-butyrylamino-7,7-dimethyl-7,8-dihydro-5H-pyrano4,3-b]thieno3,2-e]- pyridine-2-carboxamides depending on steric hindrance in the amines.
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