热凝固致良性前列腺增生组织在590～1 064 nm的吸收和散射特性的变化

研究了自然的和热凝固的良性前列腺增生(BPH)组织在590～1 064 nm光谱范围的光学特性及其差异，实验采用带积分球附件的分光光度计以及反向倍增法获取组织样品的吸收和散射特性参数。结果表明：热凝固导致BPH组织在590～1 064 nm光谱范围的吸收系数明显地减小的，自然的和热凝固的BPH组织的吸收系数都有一个峰值在990 nm处，其值分别为0.438和0.416 mm-1,自然的和热凝固的BPH组织的吸收系数的最大差异在1 064 nm，其值为86.79%，其最小差异在920 nm，其值为4.74%。热凝固导致BPH组织在600～1 064 nm光谱范围的约化散射系数明显地增大，而在590 nm处，热凝固导致BPH组织的约化散射系数却是明显地减小，自然的和热凝固的BPH组织的约化散射系数都有一个峰值在970 nm处，其值分别为1.090和1.449 mm-1,其另一个峰值都在1 050 nm处，其值分别为1.116和1.627 mm-1,自然的和热凝固的BPH组织的约化散射系数的最大差异在1 060 nm，其值为47.73%，其最小差异在600 nm，其值为4.86%。

Thermal Coagulation of Human Benign Prostatic Hyperplasia Tissues Induced Changes in the Absorption and Scattering Properties in Spectral Range from 590 to 1 064 nm in vitro

The optical properties and their differences of native and coagulated human benign prostatic hyperplasia(BPH) tissues were studied in the spectral range from 590 to 1 064 nm in vitro.The measurements were performed using a spectrophotometer with an integrating sphere attachment,and the absorption and scattering properties were assessed from these measurements using the inverse adding-doubling method.The results of measurement showed that the thermal coagulation of BPH tissues induced obviously the decrease in the absorption coefficients in the spectral range from 590 to 1 064 nm.The peaks in the absorption coefficients for native and coagulated BPH tissues were respectively 0.438 and 0.416 mm-1 corresponding to the same wavelength of 990 nm,the maximum difference in the absorption coefficients of native and coagulated BPH tissues is 86.79% at 1 064 nm,and the minimum difference is 4.74% at 920 nm.The thermal coagulation of BPH tissues induced an increase in the reduced scattering coefficients in the spectral range from 600 to 1 064 nm obviously,and induced a decrease in the reduced scattering coefficients at 590 nm obviously.The peaks in the reduced scattering coefficients for native and coagulated BPH tissues were respectively 1.090 and 1.449 mm-1 corresponding to the same wavelength of 970 nm,and other peaks in the reduced scattering coefficients for native and coagulated BPH tissues were respectively 1.116 and 1.627 mm-1 corresponding to the same wavelength of 1 050 nm,the maximum difference in the reduced scattering coefficients of native and coagulated BPH tissues is 47.73% at 1 064 nm,and the minimum difference is 4.86% at 600 nm.