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An efficient synthesis of Baylis-Hillman adducts of acrylamide: Pd-catalyzed hydration of Baylis-Hillman adducts of acrylonitrile
Authors:Eun Sun Kim
Affiliation:Department of Chemistry and Institute of Basic Science, Chonnam National University, Gwangju 500-757, Republic of Korea
Abstract:An efficient palladium-catalyzed two-step protocol for the synthesis of Baylis-Hillman adducts of acrylamide was developed. The method involved the preparation of Baylis-Hillman adducts of acrylonitrile and a Pd-catalyzed hydration of nitrile with acetaldoxime.
Keywords:Baylis-Hillman adducts   Palladium   Nitrile   Hydration   Amide   Acetaldoxime
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