A Facile and Practical Process for the Synthesis of Polysubstituted Furans from Alkynes Using Atmospheric Oxygen as a Terminal Oxidant |
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| Authors: | Jingxiu Xu Xingdong Song Jinwu Zhao |
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| Institution: | School of Pharmacy, Guangdong Medical College, Dongguan, Guangdong 523808, China |
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| Abstract: | We present here a facile and practical procedure for the synthesis of tetrasubstituted furans from alkynes catalyzed by palladium acetate together with cupric acetate in acetic acid, using atmospheric oxygen as a terminal oxidant. Various internal aromatic alkynes afforded the target furans in satisfactory yield. |
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| Keywords: | furan alkyne palladium copper oxygen |
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