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Synthesis of isomeric 2-oxazolidinones from (1<Emphasis Type="Italic">R</Emphasis>,2<Emphasis Type="Italic">R</Emphasis>)-and (1<Emphasis Type="Italic">S</Emphasis>,2<Emphasis Type="Italic">S</Emphasis>)-2-amino-1-(4-nitrophenyl)-1,3-propanediols
Authors:M Madesclaire  V P Zaitsev  J V Zaitseva  S Kh Sharipova
Institution:(1) Faculté de Farmacie, Université d’Auvergne, Clermont-Ferrand, France;(2) Samara State University, 443011 Samara, Russia
Abstract:A synthesis is reported for (4R,5R)-and (4S,5S)-4-hydroxymethyl-5-(4-nitrophenyl)oxazolidin-2-ones and (1′R,4R)-and (1′S,4S)-4-hydroxy(4-nitrophenyl)methyl]oxazolidin-2-ones from (1R,2R)-and (1S,2S)-2-amino-1-(4-nitrophenyl)-1,3-propanediols. The effect of the experimental conditions on the formation of these compounds was studied. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1562–1570, October, 2007.
Keywords:(1R  2R)-and (1S  2S)-2-amino-1-(4-nitrophenyl)-1  3-propanediols  (4R  5R)-and (4S  5S)-4-hydroxymethyl-5-(4-nitrophenyl)oxazolidin-2-ones  (1′  R  4R)-and (1′  S  4S)-4-[hydroxy(4-nitrophenyl)-methyl]oxazolidin-2-ones
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