Free-radical annelation in the synthesis of bicyclic β-lactams. 1. Synthesis of 8-oxo-5-oxa-1-azabicyclo[4.2.0]octane and 9-oxo-6-oxa-1-azabicyclo[5.2.0]nonane derivatives |
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Authors: | Mario D. Bachi Christian Hoornaert |
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Affiliation: | Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot, Israel |
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Abstract: | A new method for the synthesis of some fused bicyclic β-lactams based on the completion of the molecular backbone by a free-radical CC bond forming reaction is described. |
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