Enantioselective Morita-Baylis-Hillman (MBH) reaction promoted by a heterobimetallic complex with a Lewis base |
| |
| Authors: | Katsuya Matsui |
| |
| Affiliation: | The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki, Osaka 567-0047, Japan |
| |
| Abstract: | ![]()
A new double-activation catalysis is presented for the Morita-Baylis-Hillman (MBH) reaction of an α,β-unsaturated ketone and an aldehyde by the combined use of a heterobimetallic asymmetric complex and tributylphosphine ((n-Bu)3P) to afford the α-methylene-β-hydroxy ketone with up to 99% ee. |
| |
| Keywords: | Double-activation Morita-Baylis-Hillman (MBH) reaction |
| 本文献已被 ScienceDirect 等数据库收录！ |
