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Alkynylation of N-tosylimines with aryl acetylenes promoted by ZnBr2 and N,N-diisopropylethylamine in acetonitrile
Authors:Ka Young Lee
Affiliation:Department of Chemistry and Institute of Basic Sciences, Chonnam National University, Kwangju 500-757, South Korea
Abstract:We found a suitable condition for the effective alkynylation of N-tosylimines with aryl acetylenes. The reaction of N-tosylimines and aryl acetylenes in the presence of ZnBr2 and DIEA (N,N-diisopropylethylamine) in CH3CN afforded the desired N-tosyl propargylamines in moderate to good yields.
Keywords:Alkynylation   N-Tosylimines   Aryl acetylenes   ZnBr2   DIEA
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