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Novel lignans from the stems and leaves of Trachelospermum jasminoides
Authors:Ling Jinga  b  Neng Jiang Yua  Yu Shan Lib  Le Fua  b  Yi Min Zhaoa a Institute of Pharmacology  Toxicology  Academy of Military Medical Sciences  Beijing  China b
Affiliation:a Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;b School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110016, China
Abstract:Two novel 5-methoxydibenzylhydroxybutyrolactone lignans named 5-methoxytracheloside and 5-methoxytrachelogenin were isolated from the stems and leaves of Trachelospermum jasminoides(Lindl.) Lem.,their structures were determined as(8S,8’S)-8’- hydroxy-3,3’,4,5-tetramethoxylignan-9,9’-olide-4’-O-β-D-glucopyranoside and(8S,8’S)-4’,8’-dihydroxy-3,3’.4,5-tertramethoxylignan -9,9’-olide by various spectroscopic analysis.5-Methoxytracheloside was a new compound and 5-methoxytrachelogenin was isolated from natural source for the first time.
Keywords:Trachelospermum jasminoides  5-Methoxytracheloside  5-Methoxytrachelogenin
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