Novel lignans from the stems and leaves of Trachelospermum jasminoides |
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Authors: | Ling Jinga b Neng Jiang Yua Yu Shan Lib Le Fua b Yi Min Zhaoa a Institute of Pharmacology Toxicology Academy of Military Medical Sciences Beijing China b |
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Affiliation: | a Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;b School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110016, China |
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Abstract: | Two novel 5-methoxydibenzylhydroxybutyrolactone lignans named 5-methoxytracheloside and 5-methoxytrachelogenin were isolated from the stems and leaves of Trachelospermum jasminoides(Lindl.) Lem.,their structures were determined as(8S,8’S)-8’- hydroxy-3,3’,4,5-tetramethoxylignan-9,9’-olide-4’-O-β-D-glucopyranoside and(8S,8’S)-4’,8’-dihydroxy-3,3’.4,5-tertramethoxylignan -9,9’-olide by various spectroscopic analysis.5-Methoxytracheloside was a new compound and 5-methoxytrachelogenin was isolated from natural source for the first time. |
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Keywords: | Trachelospermum jasminoides 5-Methoxytracheloside 5-Methoxytrachelogenin |
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