High-density doxorubicin-conjugated polymeric nanoparticles via ring-opening metathesis polymerization |
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Authors: | Bertin Paul A Smith DeeDee Nguyen SonBinh T |
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Affiliation: | Department of Chemistry and Center for Nanofabrication and Molecular Self-Assembly, Northwestern University, Evanston, IL 60208-3113, USA. |
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Abstract: | High-density doxorubicin-conjugated polymeric nanoparticles are prepared via ring-opening metathesis polymerization and sustained release of nearly 50% of the anticancer agent is observed after 24 h in mildly acidic aqueous solution. |
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