Synthesis of oligonucleotides possessing versatile probes for PET labelling and their rapid ligand-free click reaction |
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| Authors: | Shiraishi Takao Kitamura Yoshiaki Ueno Yoshihito Kitade Yukio |
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| Institution: | United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan. |
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| Abstract: | We synthesised aryl acetylene derivatives as versatile probes for labelling of oligonucleotides. RNA oligomers bearing an aryl acetylene molecule rapidly reacted with benzylazide derivatives under ligand-free click reaction conditions. |
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