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First stereoselective total synthesis of helicascolides A and C |
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| Authors: | Palakodety Radha Krishna Venkata Satyanarayana MallulaPendyala Venkata Arun Kumar |
| Affiliation: | D-211, Discovery Laboratory, Organic & Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India |
| Abstract: | The first total synthesis of helicascolides A and C is reported via acid catalyzed acetonide deprotection followed by intramolecular lactonization in one-pot as the key step. |
| Keywords: | Helicascolides A and C δ-Lactone 1,3-Syn-diol Rychnovsky&rsquo s analogy Intramolecular lactonization |
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