Daturacin, a new withanolide from Datura innoxia |
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| Authors: | Siddiqui Bina S Arfeen Shamsul Begum Sabira Sattar Fouzia A |
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| Institution: | International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, and Dr. Panjwani Center for Molecular Medicine and Drug Research, University of Karachi, Karachi-75270 Pakistan. bina@khi.comsats.net.pk |
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| Abstract: | The methanolic extract of the aerial parts of Datura innoxia afforded a new withanolide, daturacin, the structure of which was elucidated as (20R, 22S)-21,24-epoxy-1,6-dioxo-14alpha-methoxy-5beta-witha-2,25(27)-dienolide (1) by an analysis of the spectroscopic data, including extensive NMR experiments. |
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