| Abstract: | A series of 2,3‐dimethyl‐4‐(1‐acyloxy)alkoxy‐6‐tert‐butyl‐8‐fluoroquinolines were synthesized by 4‐(tert‐butyl)aniline as the starting material via acylation, substitution, and hydrolysis, and their structures were characterized by 1H NMR, 13C NMR, and HRMS. The fungicidal activity showed that compounds 6c , 6e , and 6f had excellent activity against Sphoaerotheca fuliginea with EC50 values of 38.62, 6.77, and 50.35 mg/L, respectively. The results suggest that this chemotype of compounds warrant further studies as promising fungicide. |
