Reductive Amination of Aldehydes and Ketones in a Heterogeneous System in THF and under Solvent-Free Conditions Using Sodium Borohydride-Silica Phosphoric Acid |
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| Authors: | Heshmatollah Alinezhad Mahmoud Tajbakhsh Roja Enayati Ahangar |
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| Institution: | (1) Department of Chemistry, Mazandaran University, Babolsar, Iran |
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| Abstract: | Summary. A chemoselective, fast, efficient, and high yielding method for the preparation of amines by reductive amination of aldehydes
and ketones using sodium borohydride in the presence of silica phosphoric acid in THF and under solvent-free conditions at room temperature is described. |
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| Keywords: | , Silica phosphoric acid, Reductive amination, Aldehydes, Ketones, NaBH4, |
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