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FeCl_3: Highly Efficient Catalyst for Synthesis of α-Amino Nitriles
Authors:Heravi Majid M  Ebrahimzadeh Mojgan  Oskooie Hossein A  Baghernejad Bita
Institution:1. Fax: 00982188047861;2. Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, Iran
Abstract:α‐Amino nitriles are synthesized by the three‐component coupling reaction of aldehydes, amines and trimethylsilyl cyanide using FeCl3 as a solid acid catalyst, under solvent‐free conditions in good yields. The catalyst was recovered by simple filtration and was recycled in subsequent reactions.
Keywords:one‐pot  FeCl3  trimethyl silyl cyanide  α‐aminonitriles
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