FeCl_3: Highly Efficient Catalyst for Synthesis of α-Amino Nitriles |
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Authors: | Heravi Majid M Ebrahimzadeh Mojgan Oskooie Hossein A Baghernejad Bita |
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Institution: | 1. Fax: 00982188047861;2. Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, Iran |
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Abstract: | α‐Amino nitriles are synthesized by the three‐component coupling reaction of aldehydes, amines and trimethylsilyl cyanide using FeCl3 as a solid acid catalyst, under solvent‐free conditions in good yields. The catalyst was recovered by simple filtration and was recycled in subsequent reactions. |
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Keywords: | one‐pot FeCl3 trimethyl silyl cyanide α‐aminonitriles |
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