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Marine Algae-PLA composites as de novo alternative to porcine derived collagen membranes
Authors:S Sayin  T Kohlhaas  S Veziroglu  EŞ Okudan  M Naz  S Schröder  EI Saygili  Y Açil  F Faupel  J Wiltfang  OC Aktas  A Gülses
Institution:1. Marine Science and Technology Faculty, Iskenderun Technical University, 31200, Iskenderun, Hatay, Turkey;2. Department of Oral and Maxillofacial Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3, 24105, Kiel, Germany;3. Chair for Multicomponent Materials, Institute for Materials Science, Faculty of Engineering, Kiel University, Kaiserstr. 2, 24143, Kiel, Germany;4. Faculty of Fisheries, Akdeniz University, Dumlup?nar Bulvar?, 07058, Antalya, Turkey;5. Department of Medical Biochemistry, SANKO University, Sehitkamil, 27090, Gaziantep, Turkey;6. Department of Metallurgical and Materials Engineering, Middle East Technical University (METU), 06800 Ankara, Turkey
Abstract:Resorbable and volume-stable collagen matrices have been preferred as grafting materials for diverse clinical applications in recent years. On the other hand, there is always an existing risk of transmission of infection with the cells or the tissues of the graft in using such collagen matrices. Moreover, considering the economic aspects, there is also a need for cost-efficient alternative materials. In this sense, marine algae can be considered as alternatives since they represent vast and cheap source of potential biopolymers. This work covers a comprehensive cytocompatibility study of composite biopolymers derived from different types of marine algae.
Keywords:Marine algae  Biopolymers  Tissue engineering  Cytotoxicity  Graft materials
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