Abstract: | Oximation of ortho-substituted phenylbenza]acridinones using hydroxylamine hydrochloride, sodium hydroxide and ethanol as the solvent gave always the benzoquinacridine N-oxide 2 . Oximation of para-substituted phenylbenza]acridinones, however, gave only the corresponding oximes. The structure of all products was corroborated by ir, 1H and 13C-nmr and mass spectral data. Theoretical calculations support the experimental findings. |