Determination of the Lipophilicity of Twenty-Seven Imidazo[2,1-c][1,2,4]triazine Derivatives with Strong Biological Activity by Reversed-Phase TLC. Comparison with Results Obtained by Use of Computational Algorithms |
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Authors: | Komsta Łukasz Sztanke Krzysztof Mączka Paulina Ucherek Marzena Skibiński Robert Gumieniczek Anna |
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Affiliation: | 13.Department of Medicinal Chemistry, Faculty of Pharmacy, Medical University of Lublin, Jaczewskiego 4, 20-090, Lublin, Poland ;23.Department of Medical Chemistry, Faculty of Medicine, Medical University of Lublin, Staszica 4, 20-081, Lublin, Poland ;33.Department of Organic Chemistry, Faculty of Pharmacy, Nicolaus Copernicus University of Torun, Skiodowskiej-Curie 9, 85-094, Bydgoszcz, Poland ; |
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Abstract: | JPC – Journal of Planar Chromatography – Modern TLC - The lipophilicity, log P, of 27 novel imidazo[2,1-c][1,2,4]triazine derivatives with strong biological activity has been determined... |
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