Controlled release of drugs from CD polymers substituted with ionic groups |
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Authors: | É Fenyvesi A Ujházy J Szejtli S Potter T G Gan |
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Institution: | (1) Cyclolab R&D Lab., Ltd., P.O. Box 435, H-1525 Budapest, Hungary;(2) Medice Chem. pharm. Fabrik, Pütter GmBH, P.O. Box 2063, D-58638 Iserlohn, Germany |
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Abstract: | Various disinfecting drugs (ethacridine lactate, methylene blue, gentian violet, brilliant green, fuchsin acid, cetylpyridinium chloride) were incorporated into CD bead polymers substituted with carboxymetbyl groups and a retarded release rate was measured. These polymers were successfully used as sustained release wound powders as well as in chewing gum formulations. |
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