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Controlled release of drugs from CD polymers substituted with ionic groups
Authors:É Fenyvesi  A Ujházy  J Szejtli  S Potter  T G Gan
Institution:(1) Cyclolab R&D Lab., Ltd., P.O. Box 435, H-1525 Budapest, Hungary;(2) Medice Chem. pharm. Fabrik, Pütter GmBH, P.O. Box 2063, D-58638 Iserlohn, Germany
Abstract:Various disinfecting drugs (ethacridine lactate, methylene blue, gentian violet, brilliant green, fuchsin acid, cetylpyridinium chloride) were incorporated into CD bead polymers substituted with carboxymetbyl groups and a retarded release rate was measured. These polymers were successfully used as sustained release wound powders as well as in chewing gum formulations.
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