Kondesationen mit hydrazin-N,N′-dicarbonsäurediamidin,XXIII [1] fluorierte β-diketone als reaktionspartner

Application of a 30% aqueous potassium carbonate solution for the condensation of 1,2-hydrazinedicaboxamidine with 1,1,1-trifluoro-2,4-pentanedione leads to the formation of 4,4′-dimethyl-6,6′-bis(trifluoromethyl)-2,2′-hydrazopyrimidine, with 1,1,1-trifluoro-2,4-hexanedione to 4,4′-diethyl-6,6′-bis-(trifluoromethyl)-2,2′-hydrazopyrimidine. 2-Guanidinoamino-4-methyl-6-trifluoromethylpyridine formed as an intermediate in this reacton may be isolated, while 4-ethyl-2-guanidinoamino-6-trifluoromethylpyrimidine undergoes cyclization to yield 2-amino-5-ethyl-7-trifluoromethyl-s-triazolo1,5-a]pyrimidine.