N-Benzyl Derivatives of Leucine Esters |
| |
| Authors: | Popova L A Yurashevich N Ya Knizhnikov V A |
| |
| Institution: | (1) Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, Minsk, 220072, Belarus |
| |
| Abstract: | Leucine methyl and ethyl esters reacted with 3-bromobenzaldehyde and 4-chlorobenzaldehyde in anhydrous methanol in the presence of magnesium sulfate to afford the coresponding Schiff bases of the general formula (CH3)2CHCH2CH(COOR1)N=CHR2 R1 = CH3, C2H5, R2= 3-BrC6H4, 4-ClC6H4]. Their reduction with sodium tetrahydridoborate yielded N-benzyl derivatives (CH3)2CHCH2CH(COOR1)NHCH2R2, which were converted into N-acyl-N-benzyl derivatives (CH3)2CHCH2CH(COOR1)N(COR3)CH2R2R3= CH3, C6H5]. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
