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A new lignan from Balanophora abbreviata and inhibition of lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) expression
Authors:Hosokawa Akihiro  Sumino Megumi  Nakamura Tomonori  Yano Shingo  Sekine Toshikazu  Ruangrungsi Nijsiri  Watanabe Kazuko  Ikegami Fumio
Affiliation:Graduate School of Pharmaceutical Sciences, Chiba University, Japan.
Abstract:
Six lignans including a new lignan (1), beta-sitosterol glucopyranoside and phenylpropanoids were isolated from the whole plants of Balanophora abbreviata Bl. (Balanophoraceae). Their structures were determined by NMR, MS analysis and other spectroscopic methods. Lignans (1, 2 and 4) showed potent inhibitory activities on the lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells.
Keywords:
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