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| Novel Water Soluble Fluorescent Trimethine Indocyanines Containing N-ρ-Carboxybenzyl Group | |
| 作者姓名： | Li Qiu WANG Xiao Jun PENG* Rong ZHANG Guo Quan XU Jing Nan CUI State Key Laboratory of Fine Chemicals Dalian University of Technology Dalian |
| 作者单位： | Li Qiu WANG，Xiao Jun PENG*，Rong ZHANG，Guo Quan XU，Jing Nan CUI State Key Laboratory of Fine Chemicals，Dalian University of Technology，Dalian 116012 |
| 基金项目： | the National Natural Science Foundation of China and The Ministry of Education of China for providing financial support for this project. |
| 摘 要： | Indocyanine dyes as fluorescent labeling reagents have been used in bioanalysis1,2. Arylsulfonate indocyanine dyes 1d and 1e developed by Waggoner A. S. et al.3,4 have excellent fluorescent properties combined with good aqueous solubility, are a new generation of fluorescent label compounds for proteins, oligonucleotides and other compounds containing hydroxyl, mercaptol or primary amine groups5. However, photostability of these dyes has been a problem. Z. G. YAO et al.6 reported that p… |
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