Three novel tetracyclic triterpenoids of biogenetic interest from the leaves of Azadirachta indica |
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Authors: | Bina S. Siddiqui Farhana Afshan Shaheen Faizi |
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Affiliation: | H.E.J. Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan |
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Abstract: | From the methanolic extract of Azadirachta indica leaves, we have isolated three new tetracyclic triterpenoids of biogenetic interest, namely, melianol 1, desfurano-desacetylnimbin-17-one 2 and meliatetraone 3. The structure elucidation is based on extensive spectral studies including 1H–1H-COSY, NOESY, HMQC, and HMBC experiments. |
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Keywords: | Azadirachta indica triterpenoid nimbin |
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