Synthesis and binding ability of bile acid-based receptors for recognition of flavin analogues期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Synthesis and binding ability of bile acid-based receptors for recognition of flavin analogues

Authors:	Prosenjit Chattopadhyay

Affiliation:	Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi-110016, India

Abstract:	Novel cholaphanes 6a,b, based on lithocholic and deoxycholic acids, were synthesised through 3a,b by a sequence of reactions involving Cs-salt methodology of macrocyclisation. Cholaphanes 6a,b and acyclic steroidal receptors 3a,b bind flavin analogues via three hydrogen bonds in CHCl₃.

Keywords:	Cholaphanes Flavoenzyme Flavin mimic Isoalloxazines Molecular recognition
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