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Efficient method to prepare diethylphosphonacetamides
Authors:Federico Scaravelli  Sergio Bacchi  Ornella Curcuruto  William Maton
Institution:a Chemical Development Department, GlaxoSmithKline Medicines Research Centre, via Fleming 4, 37135 Verona, Italy
b Analytical Chemistry Department, GlaxoSmithKline Medicines Research Centre, via Fleming 4, 37135 Verona, Italy
Abstract:An efficient and versatile synthetic method is described to synthesize diethylphosphonacetamides in a single step.
Keywords:Diethylphosphonacetamides  T3P  Amide coupling  Horner-Wadsworth-Emmons Agents
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