Pressurized hot water extraction (PHWE) |
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Authors: | Chin Chye Teo Swee Ngin Tan Jean Wan Hong Yong Choy Sin Hew Eng Shi Ong |
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Institution: | 1. Natural Sciences and Science Education Academic Group, Nanyang Technological University, 1 Nanyang Walk, Singapore 637616, Singapore;2. Institute of Advanced Studies, Nanyang Technological University, Nanyang Executive Centre #02-18, 60 Nanyang View, Singapore 639673, Singapore;3. Department of Epidemiology and Public Health, Yong Loo Ling School of Medicine, National University of Singapore, 8 Medical Drive, Singapore 117597, Singapore |
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Abstract: | Pressurized hot water extraction (PHWE) has become a popular green extraction method for different classes of compounds present in numerous kinds of matrices such as environmental, food and botanical samples. PHWE is also used in sample preparation to extract organic contaminants from foodstuff for food safety analysis and soils/sediments for environmental monitoring purposes. The main parameters which influence its extraction efficiency are namely the temperature, extraction time, flow rates and addition of modifiers/additives. Among these different parameters studied, temperature is described as the most important one. It is reported that the extraction of certain compounds is rather dependent on pressurized water with different applied temperature. Thus, the stability and reduced solubilities of certain compounds at elevated temperatures are highlighted in this review. With some modifications, a scaled-up PHWE could extract a higher amount of desirable compounds from solid and powdered samples such as plant and food materials. The PHWE extracts from plants are rich in chemical compounds or metabolites which can be a potential lead for drug discovery or development of disease-resistant food crops. |
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Keywords: | Pressurized hot water extraction Temperature Green extraction Scaled-up Pilot-scale Metabolites |
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