A ratiometric fluorescent chemosensor for Al in aqueous solution based on aggregation-induced emission and its application in live-cell imaging |
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Authors: | Lu Peng Zhaojuan ZhouXiaoyan Wang Ruirui WeiKai Li Yu XiangAijun Tong |
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Institution: | Department of Chemistry, Beijing Key Laboratory for Analytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, China |
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Abstract: | A ratiometric fluorescent chemosensor 1 was developed for the detection of Al3+ in aqueous solution based on aggregation-induced emmision (AIE). The chemosensor showed the fluorescence of its aggregated state and Al3+-chelated soluble state in the absence and in the presence of Al3+, respectively, and resulted in a fluorescence ratio (I461/I537) response to Al3+ in neutral aqueous solution at a detection limit as low as 0.29 μmol L−1. The method was also highly selective to Al3+ over other physiological relevant metal ions investigated in this study. Taking advantage of its AIE characteristics, the chemosensor was successfully applied on test papers for simple and rapid detection of Al3+. Moreover, the application of 1 for the imaging of Al3+ in living cells by ratiometric fluorescence changes was also achieved. |
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Keywords: | Ratiometric fluorescent chemosensor Aggregation-induced emmision Al3+ Aqueous solution detection Live-cell imaging |
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