Colorimetric detection of sulfide based on target-induced shielding against the peroxidase-like activity of gold nanoparticles

Colorimetric recognition and sensing of sulfide with high sensitivity was proposed based on target-induced shielding against the peroxidase-like activity of bare gold nanoparticles. Significant features of the new assay system are its simplicity and cost-effectiveness. The recognition of sulfide by bare gold nanoparticles can be fulfilled in a few seconds and the assay can be accomplished in about 10 min. Furthermore, the new assay system does not require surface modification of GNPs to obtain the specificity for sulfide, and a salt-induced aggregation step is not needed. The detection limit of this method for sulfide was 80 nM. These features make this sensor a potentially powerful tool for the quantitative determination of sulfide in water samples.