催化不对称反应新发展: 不对称活化

介绍了催化不对称催化反应中的一个新概念－不对称活化(asymmetricactivation)及其研究的最新发展。运用不对称活化策略，一个光学活性的整或者甚至外消旋的催化剂可以被另一种手性活化剂(chiralactivator)选择性的活化，从而催化反应生成非外消旋产物。该方法较不对称活化(asymmetricactivation)方法的优点是被活化的催化剂能够产生较使用光学纯催化剂更高对映体过量的产物。

Recent advances in catalytic asymmetric reactions: Asymmetric activation

A new strategy for asyrrnnetric synthesis, namely asymmetric activation, is presented and some of its recent advances are reviewed. With asymmetric activation strategy, a chiral or even racemie catalyst may be selectively activated by a chiral activator to yield non - racemic products. The advantage of this approach over the deactivation strategy is that the activated catalyst can produce a greater enantiomeric excess in the products than the enantiomerically pure catalvst can alone.