Mild and eco‐friendly chemoselective acylation of amines in aqueous medium using a green,superparamagnetic, recoverable nanocatalyst

Copper‐grafted guanidine acetic acid‐modified magnetite nanoparticles (Fe₃O₄@GAA‐Cu(II)) as a green, superparamagnetic and recoverable nanocatalyst is found to promote quantitative N ‐acylation of various amines in a very short time with an equimolar amount of thioacetic acid in water at room temperature. This method is found to be highly selective for amines and not sensitive to other functional groups. Mild reaction condition, high selectivity, efficiency, simple workup and excellent yields are some of the major advantages of the procedure.