Molecular complexity from aromatics: synthesis of highly functionalized spiro δ-lactones |
| |
| Authors: | Vikrant Singh |
| |
| Institution: | Department of Chemistry, IIT-Bombay, Powai, Mumbai 400 076, India |
| |
| Abstract: | A novel, general, and efficient method has been developed for the synthesis of highly functionalized spiro δ-lactones from aromatic precursors. Our methodology involves a tandem oxidative dearomatization-rearrangement of tertiary furyl carbinols and ring-closing metathesis as key features. This method allows an access to the spirolactones attached to carbocycles of various sizes. |
| |
| Keywords: | Spirolactones Furyl alcohols Oxidative dearomatization Ring-closing metathesis Medium-sized rings |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
