|
|||||
|
|
A novel reaction between benzothiazoles and diaroylacetylenes in the presence of Meldrum’s acid: ring expansion of benzothiazoles to functionalized 1,4-benzothiazines |
|
| Authors: | Mehdi Adib Esmaeil Sheibani Hamid Reza Bijanzadeh |
| Institution: | a School of Chemistry, University College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran b Chemistry Department, Zhejiang University, Hangzhou 310027, PR of China c Department of Chemistry, Tarbiat Modarres University, PO Box 14115-175, Tehran, Iran |
| Abstract: | A novel and efficient ring expansion of benzothiazoles to functionalized 1,4-benzothiazines is described. The reactive 1:1 zwitterionic intermediates formed by addition of benzothiazoles to diaroylacetylenes were trapped with Meldrum’s acid under mild reaction conditions to produce 2-2-hydroxy-2-aryl-2H-1,4-benzothiazin-3(4H)-yliden]-1-aryl-1-ethanones in excellent yields. |
| Keywords: | Diaroylacetylenes Benzothiazoles Ring expansion Meldrum&rsquo s acid |
| 本文献已被 ScienceDirect 等数据库收录！ | |