Synthesis and structure of new 1,3,5-triazine-pyrazole derivatives |
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Authors: | Svetlana N Mikhaylichenko Saurabh M Patel Aleksey A Chesnyuk |
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Institution: | a Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, Canada M1C 1A4 b Department of Organic Chemistry, Kuban State Agricultural University, Krasnodar 350044, Russian Federation |
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Abstract: | We have studied the reaction of methylenedicarbonyl compounds with 4,6-disubstituted 2-hydrazinyl-1,3,5-triazine in order to obtain novel coupled biheterocyclic aromatic systems with potential bioactivity. Reaction conditions were studied and optimized, and a series of 4,6-disubstituted 2-(1H-pyrazolyl)-1,3,5-triazines were obtained with good yield. |
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Keywords: | Cyclization Hydrazinyl-triazines 1 3-Dicarbonyl compounds Coupled 1 3 5-triazine-pyrazole derivatives Synthesis and structure |
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