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Simultaneous determination of three 5-nitroimidazoles in foodstuffs by differential pulse voltammetry and chemometrics
Authors:Yi Guib  Yong Nian Ni  Serge Kokotc a State Key Laboratory of Food Science    Technology  Nanchang University  Nanchang   China b
Affiliation:a State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China;b Department of Chemistry, Nanchang University, Nanchang 330031, China;c Chemistry, Faculty of Science and Technology, Queensland University of Technology, Brisbane 4001, Australia
Abstract:
The voltammetric behaviour of three 5-nitroimidazoles,metronidazole,tinidazole and ornidazole,was investigated,and a method was developed for the simultaneous determination of these compounds,based on their reduction at a hanging mercury drop electrode(HMDE) in pH 8.95 buffer with differential pulse voltammetric(DPV) approach.Well defined voltammetric waves with peak potentials of -692,-640 and -652 mV were observed for these compounds,respectively.It is difficult to determine them individually from their m...
Keywords:Nitroimidazoles  Metronidazole  Tinidazole  Ornidazole  Chemometrics  Differential pulse voltammetry  
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