Microwave mediated synthesis of non-carboxylic analogues of ibuprofen with improved pharmacological activity |
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Authors: | K.V.Sujitha Balakrishna Kalluraya Adithya Adhikaria J.Ravikumarb a |
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Affiliation: | a Department of Studies in Chemistry, Mangalore University, Mangalagangothri 574199, Karnataka, India;b Department of Pharmacology, NGSM Institute of Pharmaceutical Science, Deralakkatte 574160, Karnataka, India |
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Abstract: | A series of 1,2,4-triazolo[3,4-b]-thiadiazoles were synthesized following microwave irradiation method and also by conventional method.Newly synthesized compounds were evaluated for their anti-inflammatory and analgesic activities. |
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Keywords: | Ibuprofen Microwave Thiadiazole Anti-inflammatory Analgesic |
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