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Microwave mediated synthesis of non-carboxylic analogues of ibuprofen with improved pharmacological activity
Authors:K.V.Sujitha  Balakrishna Kalluraya  Adithya Adhikaria  J.Ravikumarb a
Affiliation:a Department of Studies in Chemistry, Mangalore University, Mangalagangothri 574199, Karnataka, India;b Department of Pharmacology, NGSM Institute of Pharmaceutical Science, Deralakkatte 574160, Karnataka, India
Abstract:
A series of 1,2,4-triazolo[3,4-b]-thiadiazoles were synthesized following microwave irradiation method and also by conventional method.Newly synthesized compounds were evaluated for their anti-inflammatory and analgesic activities.
Keywords:Ibuprofen  Microwave  Thiadiazole  Anti-inflammatory  Analgesic  
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