3D打印技术制备生物医用高分子材料的研究进展

3D打印技术能够根据不同患者需要,快速精确制备适合不同患者的个性化生物医用高分子材料,并能同时对材料的微观结构进行精确控制.因此,这种新兴的医用高分子材料制备技术在未来生物医学应用(尤其是组织工程应用)中具有独特的优势.近年来,对于3D打印技术制备生物医用高分子材料的研究开发受到了越来越多的关注.不同的生物相容高分子原料被应用于3D打印技术,而这些3D成型高分子材料被用于体外细胞培养,或动物模型的软组织或硬组织修复中.本文主要介绍了近年来3D打印技术在生物医用高分子材料制备中的研究进展,并对该领域的未来应用和挑战进行了展望.

PROGRESS IN THE DEVELOPMENT OF BIOMEDICAL POLYMER MATERIALS FABRICATED BY 3-DIMENSIONAL PRINTING TECHNOLOGY

Custom-designed biomedical polymer materials can be fabricated rapidly and precisely by 3-dimensional(3D) printing technology according to the requirements of patients with various diseases.In addition,the microscopic structure of the materials can be controlled during the printing process.Therefore,this novel type of technology has unique advantages in the preparation of next generation of biomedical polymer scaffolds.In recent years,the development of biomedical polymer materials by using 3D printing technology has received increasing attention.Various biocompatible polymers have been used to construct 3D scaffolds via 3D printing,and the printed polymeric scaffolds have been tested for in vitro cell culture,soft tissues repair or hard tissue repair in animal models.This review emphasizes recent advances in the development of biomedical polymer materials made by 3D printing technology,and some future applications and challenges of the technology are discussed.