In vivo activation analysis of organ cadmium using the Tsing Hua Mobile Educational Reactor |
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Authors: | Pao-Shu Chang Chien Chung Lig-Ji Yuan Pao-Shan Weng |
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Institution: | (1) Graduate Institute of Medicine, Kaohsiung Medical College, 800 Kaohsiung, Taiwan (ROC);(2) Institute of Nuclear Science, National Tsing Hua University, 30043 Hsinchu, Taiwan (ROC) |
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Abstract: | This work describes a nuclear facility forin vivo prompt gamma activation analysis (IVPGAA) using a moderated neutron beam from a 0.1 W Tsing-Hua Mobile Educational Reactor (THMER). The IVPGAA measurement is a new technique for toxic cadmium determination in organs, which can efficiently be used in clinical diagnosis. The low-power nuclear reactor provides a total neutron flux of 3.3·104 n·cm–2·s–1 on the surface of the central vertical neutron beam tube to which a liquid phantom is positioned. The capability of such partial-body irradiation facility is demonstrated. The detection limit of cadmium in the left kidney for a skin dose equivalent of 1.66 mSv (166 mrem) was 1.34 mg in a 500-s irradiation/counting period, and the sensitivity in the left kidney was 103 counts mg–1·mSv–1. The performance of IVPGAA system using the THMER nuclear facility therefore has the advantages of mobility and feasibility with high sensitivity under low neutron and gamma doses. |
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