Synthesis of 6-(6-/8-Substituted-4-Chloro-Quinoline-3-yl)-3-Aryl-s-Triazolo[3,4-b] -1,3,4-Thiadiazoles |
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Authors: | QIAO Ren-Zhong HUI Xin-Ping ZHANG Yan XU Peng-Fei ZHANG Zi-Yi |
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Institution: | Dept, of Chemistry, National Laboratory of applied Organic Chemistry, Lanzhou University, Lanzhou 730000 |
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Abstract: | A survey of literature1] revealed that s-triazolo3,4-b]-1,3,4-thiadiazole has received much attention during recent years on account of its prominent utilization as antifugal, anti-inflammatory, analgsic and anthelmintic agents probably resulting from its planner and compact structure. In the course of the study of this ring system, we previously described a series of 3,6-disubstituted-s-triazolo3,4-b]-1,3,4-thiadiazoles which exhibited antibacterial, herbicidal and plant growth regulative activities. It is well known that quinoline derivatives are associatied with broad spectrum biological activities2]. |
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