| 天然产物退热碱和异退热碱的不对称合成进展 |
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| 引用本文： | 王芳,杜爱琴,张斌.天然产物退热碱和异退热碱的不对称合成进展[J].化学通报,2008,71(1):32-39. |
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| 作者姓名： | 王芳 杜爱琴 张斌 |
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| 作者单位： | [1]山东大学药学院,济南250012 [2]化学与化工学院,济南250100 |
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| 摘 要： | 天然产物退热碱和异退热碱以及类似结构化合物表现出优异的抗疟疾活性,且未见产生耐药性的报道.本文综述了它们的各种不对称合成方法,评价了其优缺点,并简要介绍了其衍生物的合成.
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| 关 键 词： | 退热碱 异退热碱 不对称合成 衍生物 |
| 收稿时间： | 2007-05-17 |
| 修稿时间： | 2007-07-11 |
Progress in the Asymmetrical Synthesis of Natural Product Febrifugine and Isofebrifugine |
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| Wang Fang,Du Aiqin,Zhang Bin.Progress in the Asymmetrical Synthesis of Natural Product Febrifugine and Isofebrifugine[J].Chemistry,2008,71(1):32-39. |
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| Authors: | Wang Fang Du Aiqin Zhang Bin |
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| Abstract: | Febrifugine, Isofebrifugine and their analogues exhibit potent anti-malarial activity. In this paper, asymmetrical synthesis methods of Febrifugine. Isofebrifugine and their derivatives were reviewed, and the advantages and disadvantages of these methods were evaluated. |
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| Keywords: | Febrifugine Isofebrifugine Asymmetrical synthesis Derivatives |
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