FREE RADICALS INDUCED BY PHOTOLYSIS OF FROZEN SOLUTIONS OF THYMIDINE-5'-MONOPHOSPHATE: AN ESR STUDY |
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| Authors: | Yves Lion Albert van de Vorst |
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| Affiliation: | Department of Atomic and Molecular Physics, University of Liège, Institute of Physics, Start-Tilman, 4000 Liège 1, Belgium |
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| Abstract: | Abstract— The photolysis (Δ < 220 nm) of thymidine-5'-monophosphate was studied by electron-spin resonance (ESR) in acidic and alkaline phases. In both cases, the H–addition radical at the C6 position is detected at 77°K. At 225°K, a triplet 1:2:1 is observed, which suggests a H abstraction radical from the CH3 group. When oxygen is present during irradiation, a peroxide–type radical is observed, which results partly from a reaction like R + O2→ ROO and partly from an energy transfer from thymidine-5'-monophosphate to oxygen, probably in the 1π0 state. |
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