Determination of polyethylene glycols by precipitation with iodine |
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Authors: | Francois M De Neve R |
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Institution: | Laboratorium Galenische en Magistrale Farmacie, Medische en Speciale Biochemie, Vrije Universiteit Brussel, Laarbeeklaan, 103, 1090 Brussels, Belgium. |
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Abstract: | Two methods for the determination of polyethylene glycols (PEGs) in aqueous solution by precipitation with iodine have been developed. For PEGs with molecular weight 4 x 10(3)-2 x 10(4) the excess of iodine is titrated with thiosulphate, and for PEGs with average m.w. > 2 x 10(4) turbidimetric measurement is used. Both methods are relatively simple and give accurate and reproducible results. |
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Keywords: | To whom all correspondence should be addressed |
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