A convenient and efficient synthesis of (S)-lysine and (S)-arginine homologues via olefin cross-metathesis |
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| Authors: | Timothy P. Boyle Jonathan A. Coates Stephen G. Pyne |
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| Affiliation: | a Department of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
b Avexa Ltd, 576 Swan St, Richmond, Vic. 3121, Australia |
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| Abstract: | A convenient five step synthesis of (S)-homolysine, incorporating a key olefin cross-metathesis step in the chain extension methodology, has been developed, together with a six step related synthesis of a new homologue of arginine, (S)-bishomoarginine. |
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| Keywords: | (S)-Homolysine (S)-Bishomoarginine Metathesis Cationic amino acid |
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